• SUPPORT THE SHOW AND ENJOY A PREMIUM PARACAST EXPERIENCE! Welcome to The Paracast+, five years young! For a low subscription fee, you will be able to download the ad-free version of The Paracast and the exclusive After The Paracast podcast, featuring color commentary, exclusive interviews, the continuation of interviews that began on the main episode of The Paracast. We also offer lifetime memberships! FLASH! For a limited time, you can save up to 40% on your subscription. Long-term susbcribers will receive a free coupon code for the James Fox UFO documentary "The Phenomenon," which includes 3 hours of extras, while supplies last. It's easier than ever to susbcribe! You can sign up right here!

    Subscribe to The Paracast Newsletter!

COVID-19 News

Randall

J. Randall Murphy
Staff member
UPDATE ON THE PFIZER VACCINE :

"The Pfizer vaccine uses a brand new technology called messenger-RNA, or mRNA. It has never been approved for human vaccination before. Instead of using bits of virus to provoke an immune response, the mRNA trains the immune system to target the spike protein found on the surface of the coronavirus."​
If it works, the messenger-RNA strategy is IMO actually very promising,
perhaps even better than the traditional approach.


 
Last edited:

Gene Steinberg

Forum Super Hero
Staff member
Yes, that's what's been widely publicized. The Moderna vaccine is using a similar technique. Both are shown to be roughly 95% effective in Phase 3 trials, which is above the level of efficacy of most vaccines. Very very promising.

Pfizer's product is expected to gain preliminary approval, if the data is borne out, by December 10th.

The U.S. and other countries have given many vaccine makers advance orders based on the promise of their vaccines, so they can be produced. But they have to be approved to be administered. This is being done to get more supplies into the field, although the U.S. "Operation Warp Speed" falsely implies they are doing something unique in doing what other countries have done. They aren't of course.
 

Randall

J. Randall Murphy
Staff member
Yes, that's what's been widely publicized. The Moderna vaccine is using a similar technique. Both are shown to be roughly 95% effective in Phase 3 trials, which is above the level of efficacy of most vaccines. Very very promising.

Pfizer's product is expected to gain preliminary approval, if the data is borne out, by December 10th.

The U.S. and other countries have given many vaccine makers advance orders based on the promise of their vaccines, so they can be produced. But they have to be approved to be administered. This is being done to get more supplies into the field, although the U.S. "Operation Warp Speed" falsely implies they are doing something unique in doing what other countries have done. They aren't of course.
Although very promising, there are still serious questions around the use of mRNA vaccine. For example, if it can target the receptors on the virus that allow it to bind to our cells and replicate, then it would also bind to the same receptors on other cells, and perhaps some of those cells are useful cells that our body uses to deliver important stuff that healthy cells need to live, so maybe blocking those receptors could be more dangerous than the virus itself in terms of longer term consequences. But I don't know enough about this yet to be able to answer concerns of this type. More digging required.
 

Randall

J. Randall Murphy
Staff member
You have to check the information published so far from Pfizer and Moderna.
New Vaccine Strategies

As usual, this requires looking beyond the basic press releases. I've just finished looking at the company pages about mRNA vaccines, as well as some of the basic science from other sources, and then drilled down into the mechanism that is thought to play a critical role in the success of the vaccine. I'm obviously not an expert in this, but so far, I've now gone deeper into it than the average person.

One new strategy of for these vaccines is in blocking the receptors for Neuropilin-1 ( NRP1 ), a protein that in healthy people plays a crucial role in vascular and neural development. This implies that using this vaccine on children could be a very bad idea because they grow miles of new blood vessels and neural connections as they mature; and if they're faulty, serious problems can result.

Given that children are at very low risk from COVID-19, I wouldn't vaccinate my child with this type of vaccine until all the relevant questions around its effect on vascular and neural growth and maintenance for both children and adults have been answered.

However, in fully grown adults, it could be a completely different story. It has been theorized that NRP1 inhibitor therapy, could be used to battle cancer, in particular, those in brain, prostate, and breast tumors. In the case of COVID-19, the highest risk groups are adults who also happen to have a higher risk for such cancers.

So personally, I might be one of the first to line-up to get both doses before the pandemic is over. However I would have to be sure it's the right type, and I would also have to be sure that it doesn't inhibit the maintenance of existing nerves and blood vessels, or inhibit the growth of new ones for very long, because neural and vascular growth isn't completely inactive in mature people.

 
Last edited:

Randall

J. Randall Murphy
Staff member
Britain Advises no COVID-19 Vaccines in Hospitals Without Resuscitators

According to a news bulletin here in Calgary, British health authorities have reported that people with allergies can have adverse reactions to the COVID-19 vaccine, and are advising not to administer the vaccine in hospitals without resuscitators. I haven't found any links only to cross reference this news item with yet. Those who get the vaccination here are being advised not to go anywhere for at least 20 minutes in case they experience an adverse reaction.

I have also not been able to find anyone who has considered the risk of using the mRNA vaccines with the Neuropilin-1 ( NRP1 ) blockers, on the formation of nerves and blood vessels. Any complications from this action would not likely be noticeable in the time that we have had to do the vaccine testing, but might possibly manifest as very serious complications over the course of months and years.

Important Questions About The Vaccine We Need Answered
  1. What allergies cause the most severe reaction to the vaccine?
  2. Does the vaccine block Neuropilin-1 ( NRP1 ) receptors on the SARS-CoV-2 virus, or on human cells, or both?
  3. If the vaccine blocks Neuropilin-1 ( NRP1 ) receptors on humans, what effect does it have on the normal formation and maintenance of nerves and blood vessels, particularly in children?
 
Last edited:

Gene Steinberg

Forum Super Hero
Staff member
This is something one should take up with their physicians before getting a shot. I got the impression, based on the reactions in UK, that this would tend to involve people with more severe sensitivities. With other vaccines coming online (Moderna will get emergency approval for the U.S. FDA next week they expect), there will be options for those with sensitivities one hopes.
 

Randall

J. Randall Murphy
Staff member
This is something one should take up with their physicians before getting a shot.

I doubt that even most physicians will be able to answer those questions. There hasn't been enough time to evaluate all the variables. The best anyone can do right now is make an intelligent guess. I've already heard doctors on the radio make comments about the mRNA vaccine that aren't in keeping with the science behind it. So at this point, if any doctor claims that they have all the answers, it's BS.

I got the impression, based on the reactions in UK, that this would tend to involve people with more severe sensitivities. With other vaccines coming online (Moderna will get emergency approval for the U.S. FDA next week they expect), there will be options for those with sensitivities one hopes.

Here's how the issues have appeared on my radar:
  1. First we started hearing about the rapid development of vaccines
  2. Then came the news of a relatively new type of vaccine called mRNA vaccines
  3. Then came the news that this new vaccine is over 90% effective with "no serious vaccine side effects".
  4. Then this new vaccine was passed by health officials and hundreds of millions of orders were placed.
  5. Then we started hearing that the vaccine shouldn't be given to pregnant women and those under the age of 16.
  6. Then came the recommendation that people should avoid getting pregnant for months after getting vaccinated
  7. Then we heard that there were cases of serious allergic reactions in Britain
  8. Then came a report that no vaccines should be given in hospitals without a rescuscitator
  9. Then came a list of side effects that include sore arms, fever, headaches, and fatigue
Does anyone else see a pattern here?

The questions I posed in my previous post about the effect of this mRNA vaccine on the growth and maintenance of nerves ( including neurons ) and blood vessels fits with the recommendation to avoid young and pregnant people. Sheer coincidence? Or did they know about this potential hazard before the vaccine was approved, but kept it on the down-low so as to be first out of the gate to cash-in?

Given that the admitted side effects of the vaccine are worse than the symptoms that between 40 and 90% of those who get COVID-19 will experience, what rationale is there for low-risk individuals to get the vaccine? It doesn't prevent infection, or even transmission, and the way the vaccine works doesn't even offer or facilitate immunity in people who don't get the virus.

We've also been through how the numbers on deaths from the virus have been skewed so that they look far worse than they are in reality, but saying anything about that, or alternatives to lockdowns, tends to elicit irrational criticism and shaming from the COVID Nazis. Note here that I use the term "COVID Nazi" very loosely, similar to the term "coffee nazi" and not as a literal comparison.

Although it hasn't literally reached anything near actual Nazi proportions, people have been arrested and fined thousands of dollars, had their businesses and livelihoods ruined, forced into isolation under threat of incarceration, and neighbors have been encouraged to report each other to the authorities for breaking the rules. Others have openly picked physical fights with otherwise peaceful protesters.
 
Last edited:

Randall

J. Randall Murphy
Staff member
Compensation Schemes For Victims of COVID-19 Vaccine Side Effects

Australia providing drug companies with indemnity against legal claims ... Who pays compensation if a COVID19 vaccine has rare side effects

Most Common Side Effects The Same As The Milder Symptoms of the Disease

FDA List Of Side Effects: Pfizer-BioNTech COVID-19 Vaccine

The most commonly reported side effects, which typically lasted several days:
  1. Pain at the injection site
  2. Fatigue
  3. Headache
  4. Muscle pain
  5. Chills
  6. Joint pain
  7. Fever
"Of note, more people experienced these side effects after the second dose than after the first dose, so it is important for vaccination providers and recipients to expect that there may be some side effects after either dose, but even more so after the second dose."​
Note here that these are the milder side effects. When they get serious, they can be as serious as the serious symptoms of COVID-19. The two recipients in the UK who had an allergic reaction were so serious that a caution was issued not to administer the vaccine unless the hospital had a resuscitator.

Given that between 40% and 90% of the people who contract COVID-19 experience symptoms so mild they may not even know they have it, and that this vaccine will not prevent infection or transmission to others, or even guarantee immunity, plus the longer term effects on healthy patients just aren't known, I can appreciate that healthy people in low-risk situations may not want to get injected with a substance that practically guarantees they'll feel crappy ( and who knows what else ).

  • FACT SHEET ATTACHED
  • ALSO SEE THE DATA IN THE FDA Review of Efficacy and Safety PDF ( Interesting stuff starts on page 34 )
 

Attachments

  • Pfizer-BioNTech COVID-19 Vaccine EUA Fact Sheet for Recipients.pdf
    190.6 KB · Views: 0
  • Pfizer-BioNTech-COVID-19-Vaccine-Safety.pdf
    555.9 KB · Views: 0
Last edited:

Gene Steinberg

Forum Super Hero
Staff member
It is not unusual to have flu-like symptoms even with flu vaccine. They are generally brief when they occur, and are gone within a day or so.

As to the allergic reactions, this appears to involve people who, in general, have severe reactions of that sort. And they should be careful about considering this vaccine.

There is obviously no way to predict the extent of the symptoms if one gets COVID-19. Some famous people have died from it, including Charley Pride, one of the first black country singers to become a big star. I played his recordings when I worked, once, as a DJ at a country station in Alabama. In contrast, Tom Hanks and Rita Wilson had less severe symptoms, but they still lasted a couple of weeks.
 

Randall

J. Randall Murphy
Staff member
There is obviously no way to predict the extent of the symptoms if one gets COVID-19 ...
Well, actually, the statistics for the seriousness of the disease are directly related to the age and health of a person before they are infected. So we can predict with a high degree of accuracy what will happen to most people. Yes there will be exceptions, but even those are only due to us having insufficient information about them.
Some famous people have died from it, including Charley Pride, one of the first black country singers to become a big star. I played his recordings when I worked, once, as a DJ at a country station in Alabama. In contrast ...
Charlie died at about age 86. The lifespan of the average American blacks is 75. He beat the odds by over 10 years, and it's entirely common for elderly people to die from some form of pneumonia ( the generic name for a respiratory infection ) and that is exactly what COVID-19 was originally described as.

So doesn't it make more sense to just add SARS-CoV-2 to the list of other germs that cause pneumonia, and chalk his death up to the ravages of age, than to cherry-pick this virus out of the pot? Yes. So why do it then? Could it be that it's because coronaphobia is dominating the news right now? And as with all news stories, if it bleeds it leads?

BTW, I loved Charlie's songs when I was a kid. Something about him came across to me as very genuine. He's a true legend in his genre.
 
Last edited:

Randall

J. Randall Murphy
Staff member
IMPORTANT UPDATE

The connection between neuropilins and mRNA vaccines still needs clarification. Further efforts to find a direct reference for a neuropilin strategy in the specific Pfizer mRNA vaccine now being administered only reveals related articles. I can no longer find the original article that connected the two, and the rest have separated the direct neuropilin blocker strategy and the mRNA strategy into two separate groups. This might be good news.

If the original source citing the connection was in error and retracted, it could alleviate the related concerns about blocking neuropilin receptors. So far, I have now only found a statement saying, "In theory, blocking the spike would mean people wouldn't become infected with the virus." ( source ). But it is not specific about what is doing the "blocking" when it comes to mRNA vaccines, so it could also be worse.

Presently however, the outlook seems positive. While neuropilin blockers are a vaccine strategy, it doesn't appear to be exactly the same strategy used by the Pfizer mRNA vaccine. Instead of blocking the receptors directly, it looks like it gets our immune system to do the job. So now questions remain about the effect that the antibodies that attack the virus's receptors will have on the human receptors that the virus is mimicking.

The last thing we want is for our own immune system to start attacking our own cells because it thinks they're a COVID-19 virus. That sort of thing is really serious. For example Type 1 Diabetes is exactly this type of immune system disorder. In the case of Neuropilin-1, instead of pancreatic cells, the affected cells would be nerves and blood vessels.

So are we entirely sure there's no cause for concern? I'm not so sure yet, but will post news and info as it becomes available. If anyone else can answer these sorts of questions, please add yourself to the discussion. As an aside: I'd like to know just how the SARS-CoV-2 virus managed to "mimic" a human spike protein, and what aspect of a "zoonotic"process out of the animal kingdom could account for that.





 
Last edited:

Randall

J. Randall Murphy
Staff member
COVID-19 and Human Rights - We are All In This Together
A Document From The United Nations

"COVID-19 is showing that universal health coverage (UHC) must become an imperative."​
"Countries that have invested in protecting economic and social rights are likely to be more resilient."​
"States need to be respecting and protecting, among other rights, freedom of expression and of the press, freedom of information, freedom of association and of assembly."​
"The threat is the virus, not the people. Emergency and security measures, if needed, must be temporary, proportional and aimed at protecting people."​
"This is not a time to neglect human rights; it is a time when, more than ever, human rights are needed to navigate this crisis in away that will allow us, as soon as possible, to focus again on achieving equitable sustainable development and sustaining peace."
Merry Christmas
AB_COVID_Banner-01a.jpg
United Nations Document Attached Below​
 

Attachments

  • UN_OnHumanRightsAndCOVID-19.pdf
    1.7 MB · Views: 1
Last edited:

Gene Steinberg

Forum Super Hero
Staff member
FYI: My handicapped nephew, Jaret, suffered from severe stomach symptoms beginning yesterday. It may have been food-based, and he seems better today. But his mom is testing him today to be sure. Now he isn't a child — he's in his mid 40s — but children are being impacted by the virus, although severe symptoms aren't as frequent. However, they can infect older people even if asymptomatic, including parents and grandparents, and that factor is often overlooked in saying children are immune.

As of mid-November: "While severe complications are rare among children, they are possible. Data from the Centers for Disease Control and Preventionshows 1,163 children in the U.S. have been diagnosed with a serious condition linked to Covid-19 called multisystem inflammatory syndrome. Twenty of those children have died.

"Overall in the pandemic, the AAP said the number of pediatric Covid-19 deaths has reached 133. That is a fraction — 0.06 percent — of the total number of U.S. deaths."

Bu it doesn't make those deaths any less tragic.
 

Randall

J. Randall Murphy
Staff member
FYI: My handicapped nephew, Jaret, suffered from severe stomach symptoms beginning yesterday. It may have been food-based, and he seems better today. But his mom is testing him today to be sure. Now he isn't a child — he's in his mid 40s — but children are being impacted by the virus, although severe symptoms aren't as frequent. However, they can infect older people even if asymptomatic, including parents and grandparents, and that factor is often overlooked in saying children are immune.

As of mid-November: "While severe complications are rare among children, they are possible. Data from the Centers for Disease Control and Preventionshows 1,163 children in the U.S. have been diagnosed with a serious condition linked to Covid-19 called multisystem inflammatory syndrome. Twenty of those children have died.

"Overall in the pandemic, the AAP said the number of pediatric Covid-19 deaths has reached 133. That is a fraction — 0.06 percent — of the total number of U.S. deaths."

Bu it doesn't make those deaths any less tragic.
Indeed. I'll have to take a closer look at those stats. However a death that is "linked to COVID-19" may still have no direct causal connection between COVID-19 and the cause of death. In the articles I've read, there hasn't been any deaths of healthy children as a direct result of COVID-19. But maybe those are now out of date or missed some of the evidence.
 

marduk

quelling chaos since 2352BC
COVID-19 and Human Rights - We are All In This Together
A Document From The United Nations

"COVID-19 is showing that universal health coverage (UHC) must become an imperative."​
"Countries that have invested in protecting economic and social rights are likely to be more resilient."​
"States need to be respecting and protecting, among other rights, freedom of expression and of the press, freedom of information, freedom of association and of assembly."​
"The threat is the virus, not the people. Emergency and security measures, if needed, must be temporary, proportional and aimed at protecting people."​
"This is not a time to neglect human rights; it is a time when, more than ever, human rights are needed to navigate this crisis in away that will allow us, as soon as possible, to focus again on achieving equitable sustainable development and sustaining peace."
Merry Christmas
AB_COVID_Banner-01a.jpg
United Nations Document Attached Below​
Did you see footage of the anti-masker protests downtown? With Trump 2020 flags?

Infuriating. Nauseating. So stupid.
 

Randall

J. Randall Murphy
Staff member
Did you see footage of the anti-masker protests downtown? With Trump 2020 flags? Infuriating. Nauseating. So stupid.
I didn't see the "Trump 2020" flags but I'll take your word for it that they were there someplace. I'll share your sentiment on that particular element.

However, what I have seen are photos with Canadian flags, and poster boards that say "Lockdowns Are More Deadly Than COVID" and "Let's Get Calgary Back To Work". These are valid sentiments, and what I find even more infuriating, was our pompous, presumptuous, judgmental, condescending Mayor demeaning them by labeling them as "self-indulgent", "not really standing up for their rights", and "only there to be cool".

I haven't heard a politician say something so outrageous in a civilized Western Democracy - ever. The overbearing attitude that he can see inside of the minds of a group of protesters and condemn them in public for what he thinks they believe and feel, is sick. Even if I might disagree with some elements within the protest, I have no doubt that many of them are genuinely concerned for rights and freedoms, as well as saving lives and livelihoods, by taking a non-lockdown approach, and I believe they should have every right to express their concerns without unconstructive offhanded condemnation.

In particular, whatever your views might be ( and I know we seem to have some differences here ), there are now over 50,000 medical & public health scientists and practitioners who don't agree with lockdowns either ( source ). That alone should be sufficient for any reasonably intelligent person to recognize that it is worthy of serious consideration, rather than being written off as uninformed childish opinion.
 
Last edited:

marduk

quelling chaos since 2352BC
I didn't see the "Trump 2020" flags but I'll take your word for it that they were there someplace. I'll share your sentiment on that particular element.
Yup it's wild. There were 3-4 people with them there.
However, what I have seen are photos with Canadian flags, and poster boards that say "Lockdowns Are More Deadly Than COVID" and "Let's Get Calgary Back To Work". These are valid sentiments, and what I find even more infuriating, was our pompous, presumptuous, judgmental, condescending Mayor demeaning them by labeling them as "self-indulgent", "not really standing up for their rights", and "only there to be cool".
I hate Nenshi, but he's right about this. Lockdowns are not more deadly than Covid. They are damaging, to be sure - so we should minimize them. And the way to minimize them is to wear masks and abide by the lockdown. The more we do it, the shorter it will be, and hopefully be avoided further.

That's the problem here - people not following the rules and not being stringent enough with enforcement (or the policy itself) has lead to more and longer lockdowns. Simply because people don't want to be told what to do.

It's childish.
I haven't heard a politician say something so outrageous in a civilized Western Democracy - ever. The overbearing attitude that he can see inside of the minds of a group of protesters and condemn them in public for what he thinks they believe and feel, is sick. Even if I might disagree with some elements within the protest, I have no doubt that many of them are genuinely concerned for rights and freedoms, as well as saving lives and livelihoods, by taking a non-lockdown approach, and I believe they should have every right to express their concerns without unconstructive offhanded condemnation.
My freedom to live outweighs their freedom to protest. It's quite a simple value proposition, quite frankly. I'm glad criminal charges have been laid, as well as tickets for not obeying the bylaw.
In particular, whatever your views might be ( and I know we seem to have some differences here ), there are now over 50,000 medical & public health scientists and practitioners who don't agree with lockdowns either ( source ). That alone should be sufficient for any reasonably intelligent person to recognize that it is worthy of serious consideration, rather than being written off as uninformed childish opinion.
We all know the facts, man. The world knows the facts. Lockdowns work. Masks work. If we would have been wearing the masks and not being stupid in our province, we wouldn't have needed a lockdown in the first place. But we didn't, and now we do, and numbers are already going down.

I love you man, but right is right here.
 

Top